FIGURE 3 from The Genetic Landscape of Ocular Adnexa MALT Lymphoma Reveals Frequent Aberrations in NFAT and MEF2B Signaling Pathways

Abstract

<p>Oncoprints showing alterations occurring at any frequency in OAMZL tumors in genes belonging to MZ development pathways. <b>A,</b> BCR signaling. <b>B,</b> NF-κB signaling. Genes marked in red in <b>A</b> and <b>B</b> are found in both the BCR and NF-κB signaling pathways. <b>C,</b> NOTCH signaling. Columns correspond to individual patients while genes and their alteration frequency are listed in rows. <b>D,</b> Cooccurrence of genetic alterations of BCR, NF-κB, and NOTCH signaling pathways in individual tumors. Samples that are exclusively altered in the same set of genes shared by BCR and NF-κB signaling pathways are marked with asterisks. The color code for each type of alteration is illustrated in the figure key.</p>