Abstract
Prophylactic vaccination against human papillomavirus (HPV) is the cornerstone of the World Health Organisation global strategy to accelerate the elimination of cervical cancer as a public health problem. At the end of 2007, the first two HPV vaccines were marketed in Spain. Therefore, 15 years have passed since the start of vaccination, included in the schedule of systematic immunizations for girls. Coinciding with this anniversary, this recommendation has been extended to boys. A vaccination that therefore achieves immunisation equity, regardless of sex. The purpose of this work is to offer an update on vaccination against HPV in Spain after 5 years of the initial work previously published on the historical origins of the virus and the beginnings of this immunisation, the second (after hepatitis B) for the prevention of cancer, and of the achievements and advances obtained.
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