Field study into the efficacy of a medicinal plant based complex for management of Equine Cushings Syndrome in ageing horses

Abstract

Pituitary Pars Intermedia Dysfunction (PPID), known as Equine Cushings Syndrome, is characterized by elevated plasma glucocorticoid concentration due to adenoma or hyperplasia of the pars intermedia of the pituitary gland. Clinical signs include hirsutism, hyperhidrosis, muscle atrophy, chronic infections, polyuria, polydipsia and laminitis [1]. The dopamine agonist pergolide mesylate is the conventional therapy of choice. Compliance is poor due to expense, poor prognosis and adverse events [2].