Abstract

Background: A 3D-QSAR model of KATP channel activation by benzopyran derivatives has been developed using molecular field alignment method. The model based on pED50 values required for myorelaxant activity by 4, 6 disubstituted benzopyrans has been explored. Keywords: KATP channel activation, field based 3D-QSAR, 4, 6 di-substituted benzopyran derivatives.

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