Abstract
Combined field and laboratory studies were carried out to assess the possible role of contaminated bottom sediments to neoplastic disease in fish from eastern Lake Erie and the upper Niagara River. Correlations between sediment polycyclic hydrocarbons, neoplasms in feral fish, and the induction of neoplasms in bullheads ( Ictalurus nebulosus) by exposure to extracts of polluted sediment support the hypothesis that some fish neoplasms result from exposure to carcinogenic chemicals present in the fishes environment.
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