Abstract

By integrating effective features of multi-modality medical images to provide richer information, multi-modality medical image fusion has been substantially used in computer-aided diagnosis applications. However, many existing fusion schemes do not consider how to eliminate the effects of the noise in source medical images and cannot provide enough details and textures for disease diagnosis. To address the problems above, we propose a new fidelity-driven optimization (FDO) reconstruction and details preserving guided-based fusion method for multi-modality medical images. To overcome the influence of noise in multi-modality medical images, a rank coefficient optimization method of low-rank approximation based on weighted mean curvature is proposed to reconstruct multi-modality medical image. Moreover, we propose an iterative detail preserving guided fusion (DPGF) method to integrate more textures and detail information of source multi-modality medical images, while ensuring high signal-to noise ratios. The experimental results show that the proposed method outperforms some of the state-of-the-art fusion methods. Specifically, the extensive experiments prove that our method has high robustness for noisy medical images, which also indicates the application prospects in diagnosis applications. Supplemental material and codes of this work are publicly available at <uri>https://github.com/VCMHE/FDO_DPGF</uri>.

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