Abstract
Fibrous tumor of the breast is an underappreciated, distinctive, benign, nonrecurrent lesion of the breast. The cytological features of this condition are not well characterized. We present a case report of a 30-year-old female presenting with a hard mass in her right breast. Fine needle aspiration showed smears of low cellularity showing a few clusters and sheets of mostly uniform benign epithelial cells, some of which were lined by myoepithelial cells. Scattered bipolar bare nuclei or stromal fragments were not seen. Excision with subsequent histopathological examination revealed a well-circumscribed, heavily collagenous tumor with atrophy and replacement of the epithelial and ductal elements of the breast, and diagnosed as fibrous tumor. Being nonrecurrent, it is important to distinguish this lesion from fibromatosis of the breast.
Highlights
Fibrous tumor of the breast is a distinct disease entity characterized by a discrete breast mass composed of collagenized breast stroma along with hypoplasia of ductal and epithelial elements
We present a case of fibrous tumor of the breast with the fine needle and histopathological features and discuss its clinical significance and differential diagnosis
Minkowitz et al used the term fibrous mastopathy [2] and further delineated the disease as occuring in three progressive types: Type I—comprising of mature acini involved by scant collagenized stroma in a concentric pattern, Type II—characterized by decreased acinar tissue, with coarse collagen bundles dissecting the epithelial elements, and Type III—characterized by an almost complete disappearance of the epithelial elements, with a few remnant ductules surrounded by densely collagenized stroma
Summary
Fibrous tumor of the breast is a distinct disease entity characterized by a discrete breast mass composed of collagenized breast stroma along with hypoplasia of ductal and epithelial elements. This condition is comparatively rare and underrecognized. We present a case of fibrous tumor of the breast with the fine needle and histopathological features and discuss its clinical significance and differential diagnosis. The tumor comprised of predominantly densely collagenized stroma, with atrophic ductal and epithelial elements (Figures 4(a) and 4(b)). There was absence of vascular or pseudovascular spaces, nerves, or any lymphocytic infiltrate Based on these features, a diagnosis of fibrous tumor of the breast was given. There were large areas of calcification, which is not a recognized feature of fibrous tumor of the breast
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