Abstract
A renal biopsy in a case of systemic lupus erythematosus (SLE) nephritis presenting with both nephrotic syndrome (NS) and acute renal failure (ARF) demonstrated atypical fibrillary deposits in the glomerular mesangium and subendothelium. The size and morphology of fibrils resembled those of fibronectin (FN) glomerulopathy [1,2], as also confirmed by immunoperoxidase staining. As no familial history of FN disorders was noted, this case may represent the first report of a new kidney disease entity in the context of SLE.
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