Abstract

Fibromyalgia (FM) is a disease whose main feature is chronic generalized pain of idiopathic origin as well as fatigue, sleep disorders, and neurological symptoms. Despite its high prevalence, FM continues to pose diagnostic and therapeutic challenges for health professionals. FM develops due to multiple unique factors that include a genetic predisposition, personal experiences, emotional and cognitive factors, the mind-body relationship, and the biopsychological ability to cope with stress. Its variable nature and symptoms together with associated comorbidities make it difficult to reach an early diagnosis. The diagnostic criteria are still a matter of debate and the lack of specific tests and pathognomonic pathologies of the disease contribute to the lack of precise diagnosis. Given that the pathogenesis and continuation of this condition involve multiple components, a multimodal treatment approach is required. Despite the availability of various treatments, its management remains a challenge. An effective treatment approach should be personalized and multidisciplinary. Goals should be realistic and prioritize maintaining or improving function, improving quality of life, and managing symptoms.

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