Abstract
Fibrinolytic activity and serum lipids were determined in 44 patients with liver cirrhosis. Euglobulin clot lysis time (ELT) was shorter in patients with liver cirrhosis than in normal. And ELT was significantly shorter in cases with ascites compared with that of the compensated stage. ELT in the hemorrhage group having a ruptured esophagial varices was significantly longer than in the ascites group, and the average of hemorrhage group was the same as that of normal.There was a significant decrease in plasma fibrinogen in both groups with ascites and hemorrhage compared with the compensated group. The ascites group showed the lowest value of plasma fibrinogen. But there were no differences in FDP among three groups with compensation, ascites and hemorrhage.There was a positive correlation between plasma fibrinogen and serum triglycerides, so that plasma fibrinogen was decreasing in parallel with serum triglycerides concentration. It is suggested that both decreases of plasma fibrinogen and serum triglycerides were caused by result of reduced production as a liver dysfunction.
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