Abstract
Purpose: To compare mean surgical time and graft outcomes following pterygium excision and conjunctival autograft xation using patient's in situ autologous blood or standard brin glue-assisted conjunctival autograft adhesion. Methods: Outcomes of 44 eyes which underwent pterygium excision and conjunctival autograft with autologous blood (group I) were compared with 41 eyes that underwent brin glue-assisted conjunctival autograft (group II). Average time required for surgery and graft behaviour was noted in subsequent follow ups over 3 months. Results were compared between both groups. Results: The two groups were similar regarding age and gender. Mean surgical time required for group II was signicantly higher than that of group I (23.00 ± 1.71 min, group I; 26.37 ± 3.73 min, group II; P-value<0.001). Graft behaviour was analysed by noting incidence of graft edema, graft retraction, subconjunctival haemorrhage and recurrence at the end of 3 months. Incidence of graft edema at day 1, day 3 and day 7 did not differ signicantly between two study groups (P-value>0.05). Postoperatively, subconjunctival haemorrhage was seen in 54.5% and 53.7% cases in group I and group II respectively. At the end of day 21, none of the cases from either groups had any signicant graft edema or subconjunctival haemorrhage. Incidence of graft retraction at day 1 and day 3 was signicantly higher in Group I as compared to Group II (P-value<0.05 for all). However, none of the cases required any intervention for the same. No cases of graft loss or graft granuloma formation were noted in either groups in all the follow-ups. Recurrence rates of 2 cases (4.5%) and 3 cases (7.3%) were seen in group I and group II respectively at the end of 3 months. Conclusion: The technique employing the use of autologous blood for conjunctival autograft xation in pterygium surgery has provided safe and comparable results to brin glue. In terms of recurrence also, autologous blood is not inferior to brin glue in pterygium surgery. Autologous blood can be an excellent replacement for brin glue
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