Fibrin Breakdown Products in the Urine of Patients with Renal Disease.

Abstract

Meeting Abstracts1 May 1970Fibrin Breakdown Products in the Urine of Patients with Renal Disease.Derek D. Gellman, M.D., F.A.C.P., Esther D. Israels, M.D., Georgina R. Hogg, M.D., Ashley E. Thomson, M.D.Derek D. Gellman, M.D., F.A.C.P.Search for more papers by this author, Esther D. Israels, M.D.Search for more papers by this author, Georgina R. Hogg, M.D.Search for more papers by this author, Ashley E. Thomson, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-72-5-805_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe deposition of fibrin in the glomeruli is a common histological finding in renal disease. It is to be expected that breakdown products of fibrinogen and fibrin might find their way into the urine. Fibrinogen breakdown products were measured in the urine of 47 patients with a variety of renal diseases, predominantly the glomerulonephritides. These patients were studied by standard nephrological techniques including renal biopsy. Fibrinogen breakdown products were assayed by a hemagglutination-inhibition technique sensitive to a level of 4 μg/100 ml. Normal urine contains no measurable breakdown products.Fibrinogen breakdown products were found in the urine in 28 patients.... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Winnipeg, Manitoba Canada PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 May 1970Volume 72, Issue 5Page: 805-805KeywordsBiopsyFibrinFibrinogenGlomerulonephritisRenal diseasesUrine Issue Published: 1 May 1970 PDF downloadLoading ...