Abstract
CONGO RED-NEGA TIYE fibrillar deposits in the kidney have been described in the literature in the past 4 years. I,2 Using electron microscopy, Alpers et all described fibrillary glomerulonephritis as random fibrillar material in the mesangium and capillary walls that stains Congo red-negative. Fluorescence microscopy of this fibrillar material showed granular deposits of immunoglobulin and complement in the same distribution. Similarly, Korbet et at2 described immunotactoid glomerulopathy with pathologic features identical to those found in fibrillary glomerulonephritis. We present the case of an asymptomatic 66year-old woman with fibrillary glomerulonephritis on renal biopsy and laboratory evidence of a positive antinuclear antibody (ANA) titer, as well as persistent hypocomplementemia. This case is unique in that our patient has persistent hypocomplementemia, indicating a possible association of fibrillary glomerulonephritis with systemic disease.
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