Fiber pathways and cortical connections of preoccipital areas in rhesus monkeys

Abstract

An understanding of visual function at the cerebral cortical level requires detailed knowledge of anatomical connectivity. Cortical association pathways and terminations of preoccipital visual areas were investigated in rhesus monkeys by using the autoradiographic tracing technique. Medial and adjacent dorsomedial preoccipital regions project via the occipitofrontal fascicle to the frontal lobe (dorsal area 6, and areas 8Ad, 8B, and 46); via the dorsal portion of the superior longitudinal fascicle (SLF) to dorsal area 6, area 9, and the supplementary motor area; and via the cingulate fascicle to area 24. In addition, medial and dorsomedial preoccipital areas send projections to parietal (areas PGm, PEa, PG-Opt, and POa) and superior temporal (areas MST and MT) regions. In contrast, connections from the dorsolateral, annectant, and ventral preoccipital regions are conveyed via the inferior longitudinal fascicle (ILF) to the parietal lobe (areas POa and IPd), superior temporal sulcus (areas MT, MST, FST, V4t, and IPa), inferotemporal region (areas TEO and TE1-TE3), and parahippocampal gyrus (areas TF, TH, and TL). The central-lateral preoccipital region projects via an ILF-SLF pathway to frontal area 8Av. The preoccipital areas also have caudal connections to occipital areas V1, V2, and V3. Finally, preoccipital regions are interconnected via different intrinsic pathways. These findings provide further insight into the nature of preoccipital fiber pathways and the connectional organization of the visual system.