Abstract

This review summarizes principles and current stage of development of fiber-optic chemical sensors (FOCS) and biosensors (FOBS). Fiber optic sensor (FOS) systems use the ability of optical fibers (OF) to guide the light in the spectral range from ultraviolet (UV) (180 nm) up to middle infrared (IR) (10 µm) and modulation of guided light by the parameters of the surrounding environment of the OF core. The introduction of OF in the sensor systems has brought advantages such as measurement in flammable and explosive environments, immunity to electrical noises, miniaturization, geometrical flexibility, measurement of small sample volumes, remote sensing in inaccessible sites or harsh environments and multi-sensing. The review comprises briefly the theory of OF elaborated for sensors, techniques of fabrications and analytical results reached with fiber-optic chemical and biological sensors.

Highlights

  • The progress in photonics, information technology and biotechnology has involved an investigation of new sensor systems employing optical fibers

  • This review summarizes principles and current stage of development of fiber-optic chemical sensors (FOCS) and biosensors (FOBS)

  • The review comprises briefly the theory of optical fibers (OF) elaborated for sensors, techniques of fabrications and analytical results reached with fiber-optic chemical and biological sensors

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Summary

Introduction

The progress in photonics, information technology and biotechnology has involved an investigation of new sensor systems employing optical fibers. In case of intrinsic FOS, parameters of guided light are more or less altered by the physical-optical, chemical or biological parameters of the surrounding environment of the core of the OF. Those parameters can include the refractive index, concentration of chemical or biological elements, pH, pressure and temperature. The development and investigation of fiber optic chemical sensors (FOCS) and biosensors (FOBS) has been reflected by more than thousands references devoted to this field in 2002–2015 reviewed in [1,2,3,4,5,6,7,8,9]. The subdivisions deal with the narrow field of enzymatic sensors with optical oxygen transducers and whole cell sensors for monitoring environmental pollution

Optical Fibers for Chemical Sensors and Biosensors
Light Propagation in Optical Fibers and Optical Fiber Elements
Components of FOCS
FOCS for Medical and Biological Applications
Enzymatic Optical Fiber Sensors with an Oxygen Transducer
Whole Cell Optical Fiber Sensors
Biosensors of Pollutants and Toxic Compounds with Natural Cells
Multi-Wavelength Fluorescence Spectroscopy of Microorganisms
FOBS with Genetically Engineered Bioreporters
FOBS with Immobilized Living Bioluminescent Bioreporters
Findings
Immobilization of Biologicals for FOBS
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