Abstract
The replication of yeast nuclear DNA was examined by DNA fiber autoradiography. We found that yeast chromosomes contain multiple initiation sites for DNA synthesis. DNA is replicated bidirectionally from these sites at a rate of approx. 0.7 μm/min/replication fork at 24 °C. In these respects DNA replication in this simple eucaryote is similar to DNA replication in mammalian cells.
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