Abstract
Background and Aims: Familial hypercholesterolemia (FH) is the most common autosomal dominant inherited dyslipidaemia. FH is treatable with low-cost lipid lowering therapies, leading to a substantial reduction in premature coronary artery disease (CAD) if detected and treated early. Hence, screening for FH in young CAD is of utmost importance. Currently, the diagnostic scoring and categorisation of FH patients is primarily done manually using paper-based. The goal of this study is to develop a computer-based FH screening application (FH CatScreen) to facilitate the diagnostic scoring and categorisation of patients by medical practitioners based on Dutch Lipid Clinic Network Criteria, Simon Broome, US-MEDPED and Japanese FH Management Criteria.
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