Abstract

In 2000, colleagues from Spain appreciated that fever could evoke malignant arrhythmias in Brugada syndrome and in the years thereafter many more examples have been reported.1–5 Brugada syndrome is an inheritable arrhythmia syndrome associated with a characteristic electrocardiogram (ECG; type-1 or coved-type Brugada ECG). The pathophysiological mechanisms underlying Brugada syndrome are not yet resolved but may include depolarization or repolarization abnormalities.6 Although most patients with Brugada syndrome will not have arrhythmias during follow-up, some patients are extremely symptomatic and may die suddenly or have repetitive malignant ventricular arrhythmias.

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