Abstract

Placental insufficiency, as well as its complication intrauterine chronic fetal hypoxia, is one of the important problems of modern perinatology. At the same time, its numbers have been increasing in recent years. Purpose - Evaluation of the effect of ozone therapy on the blood circulation of the mother and fetus, fetoplacental blood flow and the degree of adaptation of the fetus to hypoxia according to the results of cardiotocography, ultrasound and dopplerometry. Material and methods: 38 pregnant women who applied to the Department of Obstetrics and Gynecology of Clinic No. 1 of the Samara State Medical University with fetoplacental insufficiency were divided into two groups according to the type of treatment: patients who received complex treatment with ozone therapy, and patients who received standard medical procedures. Results: about a third of women in each group had a combined extragenital pathology. Women in both groups were statistically comparable when compared in terms of general clinical characteristics, basic anthropometric data, extragenital diseases and reproductive history. The most common complications of childbirth were premature rupture of amniotic fluid (4 in the 1st group - 22.2% and 5-25% in the 2nd group) and acute fetal hypoxia (3-16.7% and 3-15%). Conclusion: Thus, the indicators of maternal-fetal circulation, fetoplacental circulation in women in the ozone therapy group were more positive than in the 2nd group, and the level of fetal adaptability to hypoxia was higher.

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