FETO-MATERNAL OUTCOME OF INTRAVENOUS LABETALOLAND ORAL NIFEDIPINE IN SEVERE PRE-ECLAMPSIA- A COMPARATIVE STUDY

Abstract

Introduction: Pre-eclampsia (PE) is a disorder of pregnancy characterized by the onset of high blood pressure and often a significant amount of protein in the urine. When it arises, the condition begins after 20 weeks of pregnancy. Aims and objectives: 1. to determine the efficacy and safety of oral nifedipine for treatment of severe hypertension of pregnancy compared with intravenous labetalol. 2. To compare the time taken to reach the therapeutic goal blood pressure after using intravenous labetalol & oral nifedipine in severe pregnancy induced hypertension. 3. The time taken to achieve a blood pressure of less than 150/100 mmHg. 4. To compare the maternal and perinatal outcome among the subjects using nifedepine over labetalo. Material and method: PROSPECTIVE RANDOMISED INTERVENTIONAL COMPARITIVE TRAIL. One and half year. Conclusion: Our present study compares the efficacy of oral Nifedipine and IV Labetalol in reaching the therapeutic goal. From the results of our study we can conclude that nifedipine required less time for reaching target BP as compare to labetalol. Less no of dose of nifedipine was used for the rapid control of blood pressure in severe hypertension in pregnancy. So, Nifedipine may be preferable as it is a simple, less time and is an oral regimen.