FETO-MATERNAL COMLICATIONS IN PREGANCY WITH METABOLIC SYNDROME -A HOSPITAL BASED STUDY

Abstract

Background: Being first identified by Reaven as a syndrome in 1988,[14] metabolic syndrome (MetS) is a series of metabolic disorders, including abdominal obesity, impaired glucose tolerance and insulin metabolism, hypertension, and dyslipidaemia. [1,8,9] Prepregnancy metabolic changes are not only the determinant of complications during pregnancy, after pregnancy, during postpartum life, but the reasons for inappropriate perinatal outcomes. Overweight women before pregnancy increases the risk of pregnancy complications obesity turns out to be an independent risk factor for macrosomia,cesarean section,pregnancy-induced hypertension, preterm delivery, intrauterine growth restriction, congenital malformation, intrauterine foetal death,etc. [2,7]The emergence of MetS characteristics during pregnancy may also harm the fetus.[4]This study was conducted to study the maternal and foetal outcome in pregnant women with Metabolic Syndrome. Methods: Metabolic syndrome was diagnosed by utilizing the pregnancy adaptation of MeS criteria of NCEPATP III laboratory and clinical criteria. Cases were followed throughout pregnancy till delivery and maternal and foetal complications were recorded. Results: Sample size was 100patients less than 20 weeks of gestation with metabolic syndrome and 100 controls which were normal pregnant patients less than 20 weeks of gestation without any comorbidities. The mean age was 29-32 years. The mean gestational age was 13-16 weeks. LSCS was significantly higher in cases than controls. APH, Pregnancy Induced Hypertension, Pre-eclampsia, Gestational Diabetes Mellitus was significantly higher in cases as compared to controls. Preterm, IUGR, Macrosomia was significantly higher in cases as compared to controls. Conclusion: Metabolic syndrome and its associated complications in pregnancy have a strong effect on the maternal and the fetal well-being. A careful history and examination,proper and timely investigations and proper monitoring and follow up with required medication and optimal control of all the parameters will result in better maternal and foetal outcome.