Abstract
Recent reports [1,2] have demonstrated a strong association between the first-trimester ultrasound detection of fetal structural abnormalities and aneuploidy. Offering genetic counseling and invasive prenatal diagnosis to women carrying affected fetuses is now warranted. Accordingly, ultrasound could be a useful first-trimester screening modality for detecting women at increased risk of fetal aneuploidy [2]. However, further information concerning the efficacy of first-trimester ultrasonography must be obtained before ultrasound is routinely incorporated within an obstetrical screening paradigm [31. Our patient is a 34-year-old G3P2 who was referred for counseling and chorionic villus sampling (CVS) because of advanced maternal age (35) and a child with Down’s syndrome (47,XY, +
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