Abstract
(N Engl J Med. 2021;385:177–178) Studies on prenatal surgical interventions have historically been limited due to rarity and potential maternal complications. In 2011, the Management of Myelomeningocele Study (MOMS) found neonatal benefits associated with fetal surgery, including reduced need for cerebrospinal fluid shunting and improved infant motor outcomes at 30 months of age, but also found an increased risk of premature birth and maternal complications. This study provided an important framework for studies on fetal surgery: the inclusion of short- and long-term neonatal outcomes, attention to maternal complications, careful patient selection, and the use of multiple care centers.
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