Abstract
Several fetal therapies have become standard in prenatal care; however, there are no available fetal treatment options for genetic disorders. In utero stem cell transplantation (IUTx) and in utero gene therapy (IUGT) may become recognized as viable strategies for treating selective congenital genetic disorders in the near future. The advantages and disadvantages of fetal stem cell transplantation and gene therapy are discussed. The limit of the therapeutic effects after birth must be clarified, along with the safety of treatment during the fetal period for each treatment before clinical application.
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