Abstract
Low birth weight remains an important public health problem in underdeveloped countries. In other hand, cardiometabolic diseases (CMD) as diabetes mellitus type 2 (DM2), metabolic syndrome (MS), myocardial infarction and stroke, are the fi rsts cause of morbidity and mortally in all the word and has characteristics of epidemic in undeveloped countries. Poor early nutrition has varying effects on subsequent CMD rates. The relative roles played by genetic and environmental factors and the interaction between the two remain the subject of much current debate. However, growing bodies of evidences suggest that epigenetic changes are a prime possibility.
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