Fetal MRI

Abstract

Fetal magnetic resonance imaging (MRI) is used with increasing frequency as a complementary imaging modality to ultrasound (US) in prenatal diagnosis. Fetal MRI displays the fetal, uterine, and extrauterine anatomy in ways that allow confirmation of normal anatomy and the diagnosis of pathological entities that were formerly very difficult to detect prenatally. Comparison of US views with standard orthogonal plane MR images reinforces the understanding of fetal anatomy as visualized with US. Technological advances in US equipment have allowed the recent description of subtle fetal anatomical structures. Similarly, knowledge of the MRI appearances of pathological conditions has opened opportunities for the sonographic diagnosis of entities such as brainstem malformations and alterations in the normal transient laminar pattern that occur during development of the fetal cerebrum. Fetal MRI can confirm suspicious US findings and thus add confidence in a particular prenatal diagnosis before performing invasive and interventional procedures. Specific MRI sequences can be used to add information about the chemical composition of fetal structures, such as fat, blood, and meconium. Dynamic MRI sequences have increased understanding of gestational age-dependent behavior, and assist the sonographer in assessment of fetal structural anomalies that cause abnormal movement and behavior. The technological ability of US to demonstrate very small structures complements the lower resolution of fetal MR images, whereas the ability of MR to visualize the whole fetus improves the limited views necessitated by US. Therefore, both US and fetal MRI have complementary strengths and weaknesses that can be used to full advantage in prenatal diagnosis.