Abstract

The solid phase synthesis of a heptapeptideamide with the natural sequence 5-11 of eledoisin is described. The peptide chain is built up stepwise by coupling methionine resin with tert.-butyloxy- carbonyl-amino acids. The cleavage from the resin is achieved in DMF/NH 3. After purification the activity of the peptide is equivalent to a material which was synthesized by classical methods.

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