Abstract
Ovarian Sex Cord Stromal Tumors (SCST) are a rare disease carrying a good prognosis. They generally affect young women; therefore fertility preservation is a critical issue. Fertility Sparing Surgery (FSS) showed promising results in both oncologic safety and fertility preservation. A retrospective case series involving 9 patients diagnosed with SCST and treated with fertility sparing surgery at our institution was conducted between January 2000 and May 2015. The median age was 24 years old (10 to 39). The main clinical manifestation was pelvic pain seen in seven patients. Five patients complained about menstrual cycle disorders. The nine patients went through fertility sparing surgery; seven had conservative staging and the other two had a unilateral salpingo-oophorectomy. Three patients out of nine had a pelvic unilateral lymphadenectomy. Two patients received adjuvant chemotherapy. Only two patients presented locoregional recurrence that occurred respectively after 7 and 192 months. The treatment combined chemotherapy and surgery based on mass resection. One patient achieved a natural pregnancy after the treatment. FSS seems to be a suitable approach for SCST. However, more case series and meta-analysis should be conducted.
Highlights
Sex cord stromal tumors (SCST) of the ovary are rare
SCST are considered as a low-grade disease [2] and their prognosis is associated with tumor grade and disease stage [3]
The first patient, with initially a poor differentiated tumor, relapsed with a 3cm mass in the pre-vesical peritoneum. She was treated with a complete mass excision followed by six courses of well tolerated BEP chemotherapy
Summary
Sex cord stromal tumors (SCST) of the ovary are rare. They represent approximately 7% of all primary ovarian tumors [1]. SCST are considered as a low-grade disease [2] and their prognosis is associated with tumor grade and disease stage [3]. They generally occur in young women of reproductive age [4], raising the issue of fertility sparing surgery (FSS). Our aim is to report our experience of FSS in SCST of the ovary and discuss its feasibility
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