Fertility Response and Progesterone Profile in Artificially Inseminated Crossbred Ewes following Intravaginal Application of Misoprostol and Isosorbide Mononitrate-A Preliminary Study

Fabiha Rasool,Asloob Ahmad Malik,Mohamad Naiem Banday,Hakim Athar,Farooz Ahmad Lone,Muzamil Rashid

doi:10.17582/journal.jahp/2019/7.1.25.31

Abstract

Fertility Response and Progesterone Profile in Artificially Inseminated Crossbred Ewes following Intravaginal Application of Misoprostol and Isosorbide Mononitrate-A Preliminary Study

Highlights

IntroductionEffective artificial insemination (AI) in sheep can extend the use of superior rams and reduces the risk of genital infections like vaginitis, cervicitis and endometritis which are common during natural mating (Najafi et al, 2014; Leethongdee et al, 2007).The development of artificial insemination and the subsequent genetic improvement of farm animals have led to a remarkable increase in the productivity of livestock (Najafi et al, 2014), but AI in sheep has not been very successful (Salamon and Maxwell, 2000; Anel et al, 2005)
There was no significant difference in the cervical penetrability among treatment groups and control
This study, preliminary provides an opportunity to further explore the role of Nitric oxide (NO) donors in enhancing fertility following FTAI in sheep

Summary

Introduction

Effective artificial insemination (AI) in sheep can extend the use of superior rams and reduces the risk of genital infections like vaginitis, cervicitis and endometritis which are common during natural mating (Najafi et al, 2014; Leethongdee et al, 2007).The development of artificial insemination and the subsequent genetic improvement of farm animals have led to a remarkable increase in the productivity of livestock (Najafi et al, 2014), but AI in sheep has not been very successful (Salamon and Maxwell, 2000; Anel et al, 2005). Laparoscopic intrauterine insemination has been proposed as an alternative method for AI using frozen-thawed semen with acceptable pregnancy rate (Anel et al, 2005) but its cost, technical expertise and animal welfare have limited its use under field conditions. The ovine cervix is a highly complex fibrous tubular structure with convoluted lumen (Kumar and Naqvi, 2014) having 2-7 rings (Kershaw et al, 2005), which normally act as barriers to protect the uterus from external contaminants. These cervical rings offer the greatest obstacle to the transcervical AI (TCAI).

Methods

Results

Conclusion