Abstract
The problem of prevention and treatment of infectious diseases in infectious and non-infectious clinics is one of the priorities in practical public health. The application of phage preparations, as antimicrobial medioprophylactic remedies against staphylo- and streptococcal infections seems to be an alternative to antibiotics and sulfonamide preparations. Pronounced tendency of circulating pathogenic bacterial strains towards reducing sensitivity to antibiotics, also caused by irrational use of the latter, further confirmed our decision to create a new phage preparation. Based on the conducted studies the new variant of Fersis, an active, multivalent phage preparation, consisting phages against staphylococci (S. aureus, S. epidermidis) and streptococci (S. pyogenes, S. viridians, S. sanguis, S. salivarius, S. agalacticae) causing oral cavity infectious diseases, has been prepared.
Highlights
Introduction group diseasesPyogenic streptococcus is the causative agent of pyogenic invasions of the mucous membranes, skin and deep tissues
The strains occurred in association and in case of staphylococci belonged mainly to the following species: S. aureus, S. epidermidis and S. saprophyticus and in case of streptococci: S. pyogenes, S. sanguis, S. salivarius, and S. agalacticae
As for the intraspecific differentiation of the isolated staphylococcal strains and the studied cases, staphylococci were mainly represented by S. aureus and S. epidermidis and streptococci-by S. pyogenes, S. sanguis, S. viridians, S. salivarius, S. agalacticae
Summary
Introduction group diseasesPyogenic streptococcus is the causative agent of pyogenic invasions of the mucous membranes, skin and deep tissues. Strains of staphylococci and streptococci, which cause pathological process in the human body, were isolated from patients with periodontitis, gingivitis and stomatitis diseases.
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