Abstract
Ferromagnetic resonance (FMR)-based magnetic energy dissipation potentially generates effective heating for cancer therapy in magnetic hyperthermia. We demonstrated the FMR characteristics of normal/customized Resovist® (particle sizes of 60 and 16 nm) for biomedical applications and revealed the bias magnetic field-dependent FMR spectrum in the range of 1–10 GHz under 0–2000 Oe. Moreover, an improvement in heating power was observed under the FMR condition. The maximum temperature increment rate was 2.5 °C/s, which is 10-fold greater than that of conventional magnetic hyperthermia with a frequency range of several hundred kHz. Our results indicate that magnetic hyperthermia by utilizing FMR enables the progressive study of cancer treatment.
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