Abstract
The presence of the additional heterocyclic nitrogen atoms in chiral PN ligands has an important influence on the asymmetric catalysis, and a clear trend was observed in the present research that the enantioselectivity and reactivity were significantly increased by raising the number of heterocyclic nitrogen atoms in these PN ligands. Through finely tuning the number of heterocyclic nitrogen atoms, a new family of ferrocene-based chiral phosphine-triazine ligands with three heterocyclic nitrogen atoms has been developed and successfully applied in Pd-catalyzed asymmetric allylic substitution. Up to 99% ee with 99% yield of allylic alkylation products and 94% ee of allylic amination products have been obtained by the use of ligand (R-c,S-p)-1f with a 4,6-diphenoxy-1,3,5-triazine moiety.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
