Abstract
Researchers continue to look for an improved animal model for the study of acquired subglottic stenosis. This report describes a ferret model that reliably produces 40% to 60% stenosis with a method analogous to the pathophysiology of prolonged endotracheal intubation. Unlike some previously developed animal models, this model has a low morbidity and a perioperative mortality of less than 5%. Ferrets are small, hardy animals that are inexpensive and easy to house, handle, and anesthetize. They are readily available from breeders in a uniform size, age, and sex. Their airway is disproportionately large for their body size, making them particularly well suited for the study of acquired subglottic stenosis and subsequent surgical therapy.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.