Fermentation: A Green Herbal Extraction Process for Polyphenols

Aeri Vidhu

doi:10.26717/bjstr.2020.31.005137

Abstract

Prerna and Aeri Vidhu* Author Affiliations Department of Pharmacognosy and Phytochemistry, School of Pharmaceutical Education and Research, India Received: October 28, 2020| Published: November 05, 2020 Corresponding author:Aeri Vidhu, Department of Pharmacognosy and Phytochemistry, School of Pharmaceutical Education and Research, Jamia Hamdard (Deemed to be University), New Delhi-110062, India DOI: 10.26717/BJSTR.2020.31.005137

Highlights

Since during its processing, the menstrum undergoes a gradient of rising alcohol level, it extracts a wide range of active ingredients improving the extraction from herbs comparable to other Ayurvedic medicines [2].These aqueous-alcoholic preparations are superior to tinctures for better absorption in gut being partly digested
Most of the secondary metabolites are linked to the plant cell wall through a hydroxyl (OH) or carbon-carbon bonds (C-C) linkage an additional step of hydrolysis is required in case all other extractions except fermentation
Ayurveda is one of the Indian traditional systems of medicine, that employs vast use of single as well polyherbal drugs and formulations documented in various Ayurvedic classics and Ayurvedic Formulary of India (AFI) [1,2]

Summary

Introduction

The menstrum undergoes a gradient of rising alcohol level, it extracts a wide range of active ingredients improving the extraction from herbs comparable to other Ayurvedic medicines [2].These aqueous-alcoholic preparations are superior to tinctures for better absorption in gut being partly digested. Fermentation is one amongst the herbal extraction process that undergoes enzymatic degradation of plant cell wall, followed by maceration better leaching of plant secondary metabolites from the matrix, without the application of high heat, ultra sonic wave and other radiation sources for extraction which usually degrades a number of bioactive constituents especially phenols. In this regard fermentation had came up as effective extraction method that removes undesirable toxins, release bound phenolics and convert various phenolic compounds into different metabolites, such as deglucosides, sulfoconjugates and glucuronides through phase I/II metabolism.

Results

Conclusion