Fenoxapro-P-Ethyl Induced Biochemical Changes in Fresh Water Fish Cyprinus carpio under Sublethal Exposure

Abstract

Fenoxapro-P-Ethyl is an herbicide which has wide scope of uses in agrarian fields to control weeds. The used Fenoxapro-P-Ethyl part is let off into streams which definitely influences the endurance of the fish. In the current investigation an endeavor was made to dissect the harmfulness of Fenoxapro-P-Ethyl and Freshwater fish, C. carpio were exposed to sublethal concentration (37.5µg/L) of Fenoxapro-P-Ethyl for 15, 30 and 45 days to analyze various parameters of protein metabolism in functionally different tissues. Total, structural and soluble proteins showed decrement; whereas free amino acids and the activities of protease, aspartate aminotransferase and alanine aminotransferase significantly increased in Fenoxapro-P-Ethyl exposed fish. Interestingly, ammonia content decreased but urea and glutamine increased at all periods of exposure. It was also observed that alterations steadily increased with the period of exposure and exhibited tissue specificity. Thus variation in the protein metabolism of the fish exposed to Fenoxapro-P-Ethyl indicates its toxic effect on the cellular metabolism thereby leading to impaired protein synthetic machinery. In light of the result of the current examination, it is along these lines recommended that proper measures be taken for detoxification of Fenoxapro-P-Ethyl before it is released in to streams, as it can bargain the endurance of aquatic territory subsequently bringing about the unsettling influences of aquatic biological system.