Abstract
Degradable iron (Fe) based materials have been widely investigated for fracture fixation to overcome complications of permanent implants. Our study is focused on the development of a new Fe–Mn–Cu alloy with enhanced antimicrobial properties. In this work, Fe–Mn–Cu alloys, with up to 10 wt% copper (Cu), were prepared by powder metallurgy route. Degradation behaviour of the alloys were studied using potentiodynamic polarization test which showed nearly about 6 times increase in corrosion rate for 10 wt% Cu compared to the base alloy. Addition of Cu has significantly increased microhardness for up to 5 wt% and decreased thereafter. Broth micro-dilution test showed increased antimicrobial activity with Cu addition in Fe–Mn alloy while in vitro cytocompatibility study showed more than 70% cell viability for all alloys. Present study indicates that Cu alloying in Fe–Mn makes it a suitable material for internal fracture fixation devices with enhanced antimicrobial properties.
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