Abstract

Felty syndrome is a rare nosology. Being a complication of seropositive rheumatoid arthritis, Felty syndrome develops only in 1% of patients suffering from this disease for 10 years. SF occurs most often in women aged 40–50 years. SF significantly weakens the immune system and reduces the quality of human life. On average, the life expectancy of patients with Felty syndrome is more than 10 years. But in the case of an aggressive course, a fatal outcome is possible. To date, the diagnostic criteria are the presence of antinuclear antibodies (especially antigranulocyte antibodies); detection of myeloid bone marrow hyperplasia with a shift towards immature cellular elements. Ultrasound reveals a significant enlargement of the spleen. The article talks about the main points of the clinical picture and diagnostic criteria that make it possible to identify this syndrome and adjust the therapy of patients.

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