Abstract
The present study was designed to examine the effect of specific opioid agonists on feeding behavior in neonatal chicks. The food intake of broiler chicks was significantly decreased by intracerebroventricular injection of DAMGO and β-casomorphin, μ-opioid receptor agonists, at 30-min postinjection. In contrast, both δ-opioid receptor agonists (DADLE and DPDPE) stimulated the food intake of the chick. Similar to the δ-opioid receptor agonists, food intake was elevated by the κ-opioid receptor agonist (U-50488H and U-62066) in a dose-dependent manner. These results suggest that the endogenous opioid peptides have an important role for feeding behavior in the central nervous system of chicks.
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