Abstract

A number of mammalian organs, especially those with an internal secretion, thyroid, thymus, adrenal, testis, ovary, hypophysis, liver, muscle etc. were given as food to tadpoles ofRana temporaria andesculenta. It was seen that each organ exerted a certain influence on growth and differentiation of the animals. Most striking was the influence of the thyroid food. It caused a precocious differentiation of the body, but suppressed further growth. The tadpoles began to metamorphose a few days after the first application of the thyroid and weeks before the control animals did so. The influence of the thymus was quite the opposite, especially during the first days of its application it caused a rapid growth of the animals, but postponed the final metamorphosis or suppressed it completely. The action of the other organs must be studied further before definite statements can be made. The thymus diet gave very dark, melanotic tadpoles, the adrenal diet extremely light albinos, the liver diet dark ones with a greenish tint.

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