Feeding a Low Manganese Diet to Heifers During Gestation Impairs Fetal Growth and Development

Abstract

A study was conducted to examine the effects of low dietary Mn on growth performance of pregnant heifers and fetal development of their offspring. Twenty pregnant Angus (n=9) and Simmental (n=11) heifers averaging 17 mo of age and 447.6kg of initial body weight were used in the 267-d study. Heifers were selected from a previous study examining the effects of supplemental Mn on growth and reproductive performance of heifers. Ten pregnant heifers per treatment from the control (analyzed at 15.8mg of Mn/kg of DM) and supplemental Mn (50 mg/kg of DM) treatments were randomly selected at the conclusion of the previous study to continue on their respective dietary treatments through gestation and early lactation. Serum cholesterol for the 267-d period was not affected by treatment. Whole-blood Mn concentration of heifers on d 267 was not affected by treatment. Whole-blood Mn concentration at birth was lower in calves born to control heifers than in those born to supplemented heifers. Calves born to control heifers weighed less at birth than those born to heifers receiving supplemental Mn. Calves born to control heifers suffered from varying signs of Mn deficiency, including superior brachygnathism, unsteadiness, disproportionate dwarfism, and swollen joints. Results suggest that feeding gestating heifers a diet containing 16.6mg of Mn/kg of DM is not adequate for proper fetal development. Supplementation of 50mg of Mn/kg of DM to the control diet was sufficient to overcome any signs of Mn deficiency in calves.