Fecal immunoglobulin A (IgA) antibodies to Yersinia enterocolitica in mice orally vaccinated and infected.

Abstract

Fecal immunoglobulin-A (IgA) antibodies to Yersinia enterocolitica serovar O3 strain were detected in the mice orally immunized with formalin-killed organisms. Y. enterocolitica O3 organisms were inhibited to colonize in the intestines of the mice producing fecal IgA. The fecal IgA antibodies were detected in the mice orally infected with the bacteria. When IgA was produced in the mice infected, they ceased shedding the organisms in their feces.