Abstract
Right and left insulae maintain differential specialization of cardiovascular regulation. Laowattana et al. found that cardiac outcome was worse than in patients with non-insular stroke/TIA during the year following left insular stroke. This persisted on multivariate analysis and in patients without symptomatic coronary artery disease. Right insular involvement did not affect cardiac outcomes. see page 477 Commentary by Martin A. Samuels, MD, FAAN, MACP During everyday life the heart and the other viscera are autoregulated, but in some extraordinary circumstances, the nervous system may intervene, incidentally damaging the internal organs. The heart is only one example of this phenomenon, but it is particularly salient in that its dysfunction may lead to rapid demise and because its abnormal function may be quickly recognized by EKG. For centuries people have known that acute life-threatening stressors …
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