Abstract
Introduction: Rasmussen encephalitis is a rare immune-mediated brain disorder. Intractable seizures and progressive neurologic dysfunction are based on unilateral hemispheric atrophy. Aetiology is not yet clarified. In brain biopsy lymphocytic infiltration and microglial nodules are evident. Microbiological agens are not found. Therapeutic options to stop the brain atrophy are immunmodulation or immunosuppression and should be started in the early phase of the disease. Seizures are mostly intractable despite aggressive treatment. Long term outcome depends on reaction to therapeutic interventions.
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