Features of the structural-geometric parameters of the heart changes in men with overweight and obesity depending on the functional class of chronic heart failure

Abstract

Despite advances made in treatment over recent years, chronic heart failure (CHF) remains a pathological condition with poor prognosis. Epidemiological and clinical studies have shown that the main pathogenesis of CHF is the structural and geometrical changes of the heart in LV remodeling, and the formation of myocardial dysfunction. Obesity has traditionally been considered an independent risk factor in the CHF development and progression. Aim. To study the features of the structural-geometric parameters of the heart changes in men with overweight and obesity depending on chronic heart failure (CHF) functional class (FC). 131 patients with I–III FC of the disease were examined. Conventional anthropometric indexes, overweight indices, and the degree of abdominal type of obesity were studied. Methods and results. Structural and geometric parameters of the myocardium were estimated with echocardiography. It was established that increase of the CHF FC in men with overweight and obesity was accompanied with the heart chambers dilation, left ventricle (LV) hypertrophy, valve calcination and intensification of valve regurgitation. Reduction in the prevalence of concentric myocardial hypertrophy is associated with the frequency of eccentric LV hypertrophy increase, which is prognostically less favorable. Conclusion. This demonstrates negative impact of the CHF FC increase on the cardiac remodeling in men with overweight and obesity.