Abstract
Clinical manifestations of type 1 diabetes mellitus (type 1 diabetes) in children largely depend on the age of the child and the degree of decompensation of metabolic processes at the time of its diagnosis. Early detection of diabetes and early treatment can improve the prognosis of the disease and reduce the risk of further complications and adverse outcomes.
 The purposeof this work: to identify the features of the manifestation of type 1 diabetes in children in the Perm Region, who fell ill from 2002 to 2017.
 Methods.The data of anamnesis, clinical and instrumental methods of research were analyzed in 378 patients with newly diagnosed diabetes mellitus type 1 in the period of hospitalization from 2002 to 2017 (378 people).
 Results.It is revealed that boys and girls get diabetes with the same frequency. The incidence of disease in recent years among rural residents remains at a lower level than in the cities of the region. There is a high incidence of disease throughout the year, regardless of the season. Initiating factors are infectious diseases, as well as various stressful situations. A standard examination in patients revealed changes corresponding to the state of hyperglycemia. One third of patients had ketoacidosis of varying severity. In11% of children, diabetes mellitus was suspected during routine follow-up. Among the comorbidities most frequently encountered are problems of the nervous system and other endocrine diseases. Almost a quarter of patients had burdened heredity according to type 1 diabetes. When comparing the data of anamnesis and manifestation of type 1 diabetes with the data of other regions, no significant difference was found.
Highlights
Clinical manifestations of type 1 diabetes mellitus in children largely depend on the age of the child and the degree of decompensation of metabolic processes at the time of its diagnosis
Detection of diabetes and early treatment can improve the prognosis of the disease and reduce the risk of further complications and adverse outcomes
The data of anamnesis, clinical and instrumental methods of research were analyzed in 378 patients with newly diagnosed diabetes mellitus type 1 in the period of hospitalization from 2002 to 2017 (378 people)
Summary
2. Частота встречаемости СД1 у родственников детей, % Fig. 2. The incidence of type 1 diabetes in relatives of the children, %. 1. Полученные эпидемиологические данные подplications in children. 2. Критический период манифестации СД1 у дефестации и течения сахарного диабета 1-го типа тей сместился на более ранние сроки и прояву детей на современном этапе / Материалы III Вселяется в возрасте 0–4 и 5–9 лет вне зависимости российской научной конференции молодых специот пола. 3. Клиническими особенностями СД1 у детей технологии в медицине: взгляд молодого специв Пермском крае можно считать раннее выявалиста»; Рязань, 14–15 сентября 2017 г. – Рязань, ление заболевания, даже на стадии нарушения. 4. Повышение НbА1с при невысокой гликемии во young specialists, graduate students, residents “Innoвремя установления диагноза свидетельствует vatsionnye tekhnologii v meditsine: vzglyad molodogo о длительном нарушении углеводного обмена.
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