Features of quantitative electroencephalography in multiple sclerosis patients with and without central neuropathic pain

Abstract

CONCLUSION The difference between spectral EEG patterns in MS patients with and without CNP could represent specific CNS changes related to central pain in MS patients. Data obtained and results of our previous studies in patients with brain–gut dysregulation and CNP believe the increase of spectral power in the beta-bands to be a marker of CNS pathology that cause disorders including CNP. RESULTS 2. Statistically significant differences in absolute spectral power between the groups were identified in the three frequency ranges - theta, beta1 and beta2. Group I was increased for the theta-band of the spectrum in the midtemporal right hemisphere region (T4) compared to the control group, for the beta1-band - in the temporal lobes of the right hemisphere (T6, T4, F8), for the beta2-band - in the occipital derivation in the right hemisphere (O2), parietal (P3 and P4), mid-temporal (T3 and T4), and postero-temporal (T5 and T6) lobes of both hemispheres as compared to both control and group II, and in the left occipital (O1) and right fronto-temporal (F8) lobes comparing to the control.