Features of intestinal microbiota in ulcerative colitis

Abstract

The study is dedicated to one of the most discussed problems of the last decade, not only in gastroenterology, but also in the scientific world. The more knowledge and ideas we have about the composition and function of the microbiota of the human body, in particular the microflora of the gastrointestinal tract, as one of the most populated department by microorganisms of the human body, the better we realize that we are only at the beginning of the this way. The evolution of methods for diagnosing of microbiota from microbiological method to modern molecular genetic techniques to isolate the genetic material of bacteria, of course, plays a key role in our understanding of this issue, attempts to establish the role of microorganisms in the development of diseases of various human systems. Inflammatory bowel diseases, including ulcerative colitis, belong to pathological conditions with an unclear etiology characterized by a chronic severe course, a diverse clinical picture, difficulty in establishing a diagnosis, long-term treatment. In this research with the modern diagnostic methods an attempt is made to come closer to understanding the changes that occur in the intestinal microbiota with ulcerative colitis, identifying probable etiological and pathogenetic agents, and identifying possible targets for exposure as additional methods of treating the disease.