Features of Immunological Status in Children with Pulmonary Echinococcosis in the Southern Regions of the Kyrgyz Republic

Abstract

The article presents an analysis of the results of a survey of 105 children with pulmonary echinococcosis aged 4 to 16 years who received inpatient treatment in the thoracic surgical department of the Osh Interregional Children's Clinical Hospital. The aim of the study was to study the immune status of patients suffering from lung echinococcosis. The research method was a complex immunogram, which determines the state of humoral immunity. It was revealed that the organism of a child reacts to the invasion of the parasite in the form of chronic intoxication, which manifests itself in the form of a lack of body weight, lag in physical development, adynamia, hypochromic anemia, dysproteinemia, etc. In addition, in children with combined echinococcosis, the level of total IgE is more than 4 times higher than in patients with other forms of echinococcosis of the lungs, but at the same time, without changing the number of poorly differentiated forms of T cells and their precursors. This is explained by the fact that in the body of children suffering from a combined form of echinococcosis, the immune system undergoes tremendous changes and requires special attention by the attending physician through an in-depth examination in the pre- and postoperative periods and the study of long-term results.