Abstract
The purpose of the study: to assess the features of microcirculatory blood flow.Materials and methods. A comparative assessment of microcirculation by laser Doppler flowmetry was carried out in 19 male volunteers aged 20–25 years against the background of breathing heated to 40° C oxygen-nitrogen and helium-oxygen gas mixtures.Main results. Breathing with a heated oxygen-nitrogen mixture consisted in an increase (by approximately 25–35%) of the values of the integral indicator of microcirculation against the background of a decrease in its efficiency. Switching to breathing with a heated helium-oxygen mixture «HeliOx 25/75» in all examined persons also led to an increase in the volumetric velocity of the peripheral blood flow. However, the degree of increase in the indicator (by 35–45% compared with normal breathing conditions) turned out to be significantly more pronounced than it was during breathing with a heated oxygen-nitrogen mixture. In addition, when breathing «HeliOx 25/75», starting from about the 2nd minute of breathing, an increase in the efficiency of microcirculation was observed due to an increase in the «contribution» to the blood flow reaction of its «active» (neuromyogenic) components.
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