Features of frequency domain optical coherence tomography in acute central serous chorioretinopathy

Abstract

Objective To observe the features of frequency domain optical coherence tomography (FD-OCT) in acute central serous chorioretinopathy (CSC).Methods The data of FD-OCT and fundus fluorescein angiography (FFA) of 31 patients with unilateral acute CSC were retrospectively analyzed.The FD-OCT of retinal pigment epithelial (RPE) layer at leakage points, retinal detachment area and RPE layer in the fellow eyes was documented.Results Thirty-four leakage points were detected in 31 eyes on FFA.At the sites of fluorescein leakage, FD-OCT showed that serous pigment epithelial detachment (PED) in 18leakage points (52.9%) and 17 eyes (54.8%), a small RPE protrusion in 8 leakage points (23.5%) and 8eyes (25.8%), RPE irregularity in 6 leakage points (17.6%) and 4 eyes (12.9%) and no detectable RPE abnormality in 2 leakage points (5.9%) and 2 eyes (6.5%).An RPE defect at the edge of or within the fPED was found in 7 leakage points (20.6%) and 7 eyes (22.6%).Serous retinal detachment and interruption or complete disappearance of the hyper-reflective inner/outer segment junction (IS/OS) were detected in all diseased eyes.Uneven thickness of the outer segments (OS) was found in 24 eyes (77.4%),14 of which had sagging sign.Flaking of the OS was found in 10 eyes (32.3%), multiple hyper-reflective dots on the posterior surface of the detached neurosensory retina and on the surface of the RPE were found in 8 eyes (25.8%).Among 31 fellow eyes, FD-OCT also showed RPE abnormalities in 11 eyes (35.5%),in which PED, RPE protrusion and RPE irregularity were detected in 2 (6.5%), 1 (3.2%) and 8 eyes (25.8%), respectively.Conclusions In acute CSC the FD-OCT images at leakage points of are featured by PED, RPE protrusion, RPE irregularity and no detectable RPE abnormality; in retinal detachment area FD-OCT are featured by serous retinal detachment, interruption or disappearance of IS/OS, uneven thickness of OS, flaking of OS and hyper-reflective dots on the posterior surface of the detached neurosensory retina and on the surface of the RPE. Key words: Retinal diseases/ diagnosis; Choroid diseases/ diagnosis; Pigment epithelium of eye; Tomography, optical coherence; Diagnostic imaging